| JCICM-16-02: Chinese Herbal Medicine for Irritable Bowel Syndrome - From Basic Mechanism to Clinical Cure |
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Principal Investigator: |
Prof. Joseph Sung & Dr Bian Zhao Xiang |
Project Coordinators: |
Dr Eric Ziea |
Research Partner: |
The Chinese University of Hong Kong & Hong Kong Baptist University |
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Project Background
IBS is a very common functional gastrointestinal disorder characterized by recurrent abdominal pain with disturbance in bowel habit, with high prevalence of IBS in Hong Kong and elsewhere. As a common disorder, there is no effective remedy in conventional medicine. A Chinese herbal formulation was tested in double-blind and placebo-controlled trial alongside scoring of improvements over quality of life by patients. The change in brain activation was also evaluated using functional magnetic resonance imaging (fMRI); technique.
Special Product Features / Technical Excellence
- A Chinese herbal formulation (patents pending; PRC) with indication of efficacy in Chinese male and female patients with more than 3 years history of IBS.
- An Integrated Research Clinic involving western clinicians and Chinese medicine practitioners for diagnosis and clinical research (using a validated questionnaire for quality of life assessment)
- Established rat research model for IBS
Intellectual Properties & Regulatory Filings
- Small-scale efficacy studies with both clinical and animal studies
- To enter pre-clinical development for filing IND in China and Hong Kong
- Patent pending: PRC
 Related Publications
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