JCICM-1-02 Cardiovascular: Research and Development of Chinese Medicine Products for Cardiovascular Disorders
Principal Investigator:
Prof. Albert SC Chan
Project Coordinators:
Prof. SL Chen / Prof. DJ Yang
Organisation:
The Hong Kong Polytechnic University
Project Background
This Project aims to develop three new drugs for myocardial ischemia/angina and hyperlipidemia based on Puerarin, a major active compound of Radix Puerariae (RP).JCM-01021 is a new drug consists of a chemical complex for myocardial ischemia, JCM-01022 is a Fu fang with two active components for modulation of blood lipids, whereas JCM-01023 is a structural modification of a single compound with enhanced bioavailability.
Special Product Features / Technical Excellence
Establishment of quality standards of medicinal plants through the collaboration with an established mainland GAP institute, and determination of the quality profiles for the active components
Enhanced bioavailability of carrier system-based formulations
Animal models and pharmacological research instruments for the safety and efficacy evaluation
Defined extraction, separation and debulking technologies for the CM products
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