Project Title: Research and Development of Chinese Medicine Products for Cardiovascular Disorders
Principal Investigator: Prof. Albert SC Chan
Project Coordinators:

Prof. SL Chen / Prof. DJ Yang
Organisation: The Hong Kong Polytechnic University
Key Features:  

  • Establishment of quality standards of medicinal plants through the collaboration with an established mainland GAP institute, and determination of the quality profiles for the active components

  • Enhanced bioavailability of carrier system-based formulations

  • Animal models and pharmacological research instruments for the safety and efficacy evaluation

  • Defined extraction, separation and debulking technologies for the CM products

 
 
 
Project Title:

Research and Development of A Botanical Drug Product on Anti-rheumatoid Arthritis From Chinese medicine

Principal Investigator:

Prof. Liu Liang
Project Coordinator:

Dr Zhou Hua

Organisation: Hong Kong Baptist University
Key Features:  

  • Product R&D following the regulatory requirements of the SFDA, PRC and the emerging requirements of the Chinese Medicine Council of Hong Kong

  • Product formulation based on established clinical practice and pharmacological studies

  • Quality control criteria for raw material and final drug product formulation

  • Processing and quality control strategies to assure product quality

 
 
 
Project Title:

Research and Development of a New Anti-Diabetic Product Based on Chinese Medicine
Principal Investigator:

Dr Simon CW Kwong
Project Coordinator:

Dr Ren Gui Xing

Organisation: Hong Kong Institute of Biotechnology
Key Features:  

  • A CM-based product with anti-diabetic and blood lipid lowering properties 

  • A novel process for the preparation and purification of extract(s)

  • Product development in accordance with the regulatory requirements of the SFDA, PRC

 
 
 
Project Title:

HKJCICM Shared Platform: To strengthen Chinese medicine research in pharmacognosy, supporting quality control of all HKJCICM-funded projects

Principal Investigator: Dr Xu Hong Xi
Project Coordinator:

Dr He Zhen Dan
Organisation: Hong Kong Jockey Club Institute of Chinese Medicine
Key Features:  

  • Provision of good quality extracts to support our funded projects

  • Strengthening the research competency in pharmacognosy in Hong Kong and hence, supporting quality control of Chinese medicine

  • Central co-ordination by HKJCICM for efficient use of public fund, management of protection of intellectual properties, quality assurance and dissemination of relevant technical and quality information

  • A network to promote the development and adoption of quality research methodologies, and sharing of information
 
 
 
Project Title: Geng-Shu Capsule as a Safer and More Natural Alternative for Patients of Menopausal Symptoms
Principal Investigators: Prof. Wang Jun & Prof. Hui Yong Zheng
Project Coordinators:

Dr Wu Wei Yong / Mr Sun Quan Zhong

Organisations: The Chinese University of Hong Kong & Shanghai Innovative Research Center of Traditional Chinese Medicine
Key Features:  

  • A modified recipe based on an ancient classical prescription and will be assessed by modern technology and prepared by advance extraction technology

  • Quality control of the medicinal herb will be executed according to GAP standard

  • The drug will be formulated as mini-capsule for easy administration

  • Efficient extraction procedures will be developed to assure that the herbal medicine meets the regulatory requirements
 
 
 
Project Title: Encyclopedia on Contemporary Medicinal Plants
Principal Investigators: Prof. Zhao Zhong Zhen & Prof. Xiao Pei Gen
Project Coordinator:

Ms. Fanny Hung S.J.
Organisation: Hong Kong Baptist University
Key Features:  

  • 800 kinds of natural medicinal plants, known in Hong Kong , on the Mainland and the international market

  • Publication in simplified, traditional Chinese characters, English and electronic version

  • Comprehensive and systematic compilation of natural medicinal plants for reference by local and international research community, the industry and other users
 
 
 
Project Title: Authentication and quality assessment of Chinese medicine materials by DNA and chemical technologies
Principal Investigators: Prof. P.C. Shaw & Prof. Paul But
Project Coordinator:

Dr Jiang Ren Wang
Organisation: Institute of Chinese Medicine, The Chinese University of Hong Kong
Key Features:  

  • Generate DNA sequences, chemical profiles and markers for selected Chinese medicinal plants and their related species, to promote authentication, quality assessment and trading of high quality TCM

  • To improve the technologies for speedy and accurate authentication

  • DNA sequences, chemical profiles and markers of 101 selected medicinal materials

  • Chemical markers of 10 selected medicinal materials and protocols for extraction of DNA and chemicals

  • DNA clones and chemical markers generated for future development
 
 
 
Project Title: Research and Development of a New TCM-based Antidepressant
Principal Investigators: Prof. HF Kung
Project Coordinator:

Prof. LD Kong

Organisation: The University of Hong Kong
Key Features:  

  • Research and development of an effective anti-depression Chinese medicine product

  • An innovative formulation in which the active fractions and ingredients are well documented

  • Modern extraction technology will be utilized to maximize the collection of active fractions and ingredients from Chinese medicinal herbs

  • QC methodologies including fingerprint spectra will be established to assess and assure the quality of preparation
 
 
 
Project Title: Chinese Herbal Medicine for Irritable Bowel Syndrome: From Basic Mechanism to Clinical Cure
Principal Investigators: Prof. Joseph Sung & Dr Bian Zhao Xiang
Project Coordinator:

Dr Eric Ziea

Organisation: The Chinese University of Hong Kong & Hong Kong Baptist University
Key Features:  

  • A joint effort between conventional medical practitioners and Chinese medicine practitioners.

  • Investigate a proper form of prepared Chinese medicinal herbs for the clinical and basic research for irritable bowel syndrome (IBS).

  • Evaluate the herbal medicine on sensory and motor responses and expression of neurotransmitters in a rat model of IBS and test the change in visceral sensitivity in patients with IBS after receiving herbal medicine.

  • Conduct clinical study to test the efficacy of herbal medicine in relieving symptoms and change in quality of life of patients with IBS.